Buttermilk and Krill Oil Phospholipids Improve Hippocampal Insulin Resistance and Synaptic Signaling in Aged Rats
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-0934-y
Abstract: Impaired glucose metabolism and mitochondrial decay greatly increase with age, when cognitive decline becomes rampant. No pharmacological or dietary intervention has proven effective, but proper diet and lifestyle do postpone the onset of neurodegeneration and… read more here.
Keywords: aged rats; insulin; synaptic signaling; insulin resistance ... See more keywords
Chronic administration of ketamine induces cognitive deterioration by restraining synaptic signaling
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Psychiatry"
DOI: 10.1038/s41380-020-0793-6
Abstract: The discovery of the rapid antidepressant effects of ketamine has arguably been the most important advance in depression treatment. Recently, it was reported that repeated long-term ketamine administration is effective in preventing relapse of depression,… read more here.
Keywords: administration; restraining synaptic; use; synaptic signaling ... See more keywords
Optimal synaptic signaling connectome for locomotory behavior in Caenorhabditis elegans: Design minimizing energy cost
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1005834
Abstract: The detailed knowledge of C. elegans connectome for 3 decades has not contributed dramatically to our understanding of worm’s behavior. One of main reasons for this situation has been the lack of data on the… read more here.
Keywords: optimal synaptic; connectome locomotory; energy; synaptic signaling ... See more keywords
Dysregulation of Synaptic Signaling Genes Is Involved in Biology of Uterine Leiomyoma
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.3390/genes12081179
Abstract: Uterine leiomyomas are tumors, which are hormone driven and originate from the smooth muscle layer of the uterine wall. In addition to known genes in leiomyoma pathogenesis, recent approaches also highlight epigenetic malfunctions as an… read more here.
Keywords: genes involved; signaling genes; synaptic signaling; dysregulation ... See more keywords