Binding Sites for Amyloid-β Oligomers and Synaptic Toxicity.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a024075
Abstract: In Alzheimer's disease (AD), insoluble and fibrillary amyloid-β (Aβ) peptide accumulates in plaques. However, soluble Aβ oligomers are most potent in creating synaptic dysfunction and loss. Therefore, receptors for Aβ oligomers are hypothesized to be… read more here.
Keywords: sites amyloid; toxicity; binding sites; oligomers synaptic ... See more keywords