Cell-type-specific enhancement of deviance detection by synaptic zinc in the mouse auditory cortex
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2405615121
Abstract: Significance This research provides mechanistic insight into how synaptic zinc impacts populations of cortical neurons shaping neuronal deviance detection. This research demonstrates a cell-type-specific impact of synaptic zinc on deviance detection, identifies the source of… read more here.
Keywords: cell type; deviance detection; synaptic zinc; zinc ... See more keywords
Cell-specific gain modulation by synaptically released zinc in cortical circuits of audition
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.29893
Abstract: In many excitatory synapses, mobile zinc is found within glutamatergic vesicles and is coreleased with glutamate. Ex vivo studies established that synaptically released (synaptic) zinc inhibits excitatory neurotransmission at lower frequencies of synaptic activity but… read more here.
Keywords: modulation; synaptic zinc; zinc; gain ... See more keywords