LAUSR

SynBio‐SynChem Approaches to Diversifying the Pacidamycins through the Exploitation of an Observed Pictet‐Spengler Reaction

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1 Published in 2020 at "Chembiochem"

DOI: 10.1002/cbic.202000594

Abstract: A nonenzymatic Pictet‐Spengler reaction has been postulated to give rise to a subset of naturally occurring uridyl peptide antibiotics (UPAs). Here, using a combination of strain engineering and synthetic chemistry, we demonstrate that Pictet‐Spengler chemistry… read more here.

Keywords: spengler reaction; spengler; chemistry; pictet spengler ... See more keywords