Traumatic brain injury is associated with increased syndecan-1 shedding in severely injured patients
Sign Up to like & getrecommendations! Published in 2018 at "Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine"
DOI: 10.1186/s13049-018-0565-3
Abstract: IntroductionHead injury and exsanguination are the leading causes of death in trauma patients. Hemorrhagic shock triggers systemic endothelial glycocalyx breakdown, potentially leading to traumatic endotheliopathy (EoT). Levels of syndecan-1, a main glycocalyx component, have been… read more here.
Keywords: glycocalyx; syndecan shedding; isolated tbi; tbi ... See more keywords
Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041066
Abstract: Circulating biomarkers reflecting cardiac inflammation are needed to improve the diagnostics and guide the treatment of heart failure patients. The cardiac production and shedding of the transmembrane proteoglycan syndecan-4 is upregulated by innate immunity signaling… read more here.
Keywords: inflammation; non ischemic; heart; ischemic non ... See more keywords