A simple mechanistic explanation for Barth syndrome and cardiolipin remodeling.
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DOI: 10.1002/jimd.12445
Abstract: Barth syndrome is a multisystem disorder caused by an abnormal metabolism of the mitochondrial lipid cardiolipin. In this review, we discuss physical properties, biosynthesis, membrane assembly, and function of cardiolipin. We hypothesize that cardiolipin reduces… read more here.
Keywords: mechanistic explanation; explanation barth; barth syndrome; cardiolipin ... See more keywords