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Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer’s, and Parkinson’s Diseases

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23031060

Abstract: Iron accumulates in the ageing brain and in brains with neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and Down syndrome (DS) dementia. However, the mechanisms of iron deposition and… read more here.

Keywords: ferroportin; iron; brain; ageing brain ... See more keywords