Diversity of genetic events associated with MLH1 promoter methylation in Lynch syndrome families with heritable constitutional epimutation
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DOI: 10.1038/gim.2018.47
Abstract: PurposeConstitutional epimutations are an alternative to genetic mutations in the etiology of genetic diseases. Some of these epimutations, termed secondary, correspond to the epigenetic effects of cis-acting genetic defects transmitted to the offspring following a… read more here.
Keywords: syndrome families; methylation; mlh1; families heritable ... See more keywords