CANDLE Syndrome As a Paradigm of Proteasome-Related Autoinflammation
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DOI: 10.3389/fimmu.2017.00927
Abstract: CANDLE syndrome (Chronic Atypical Neutrophilic Dermatosis with Lipodystrophy and Elevated temperature) is a rare, genetic autoinflammatory disease due to abnormal functioning of the multicatalytic system proteasome–immunoproteasome. Several recessive mutations in different protein subunits of this… read more here.
Keywords: syndrome paradigm; related autoinflammation; paradigm proteasome; candle syndrome ... See more keywords