Reduction of Werner Syndrome Protein Enhances G:C → A:T Transition by O6-Methylguanine in Human Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.8b00009
Abstract: O6-Methylguanine ( O6-MeG) is a damaged base produced by methylating reagents. The Werner syndrome protein (WRN) is a cancer-related human DNA helicase. The effects of WRN reduction on O6-MeG-caused mutagenesis were assessed by an siRNA-mediated… read more here.
Keywords: syndrome protein; meg; methylguanine; werner syndrome ... See more keywords
The Wiskott-Aldrich syndrome protein regulates antigen processing and presentation by dendritic cells
Sign Up to like & getrecommendations! Published in 2017 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.12587
Abstract: The Wiskott-Aldrich syndrome protein regulates antigen processing and presentation by dendritic cells read more here.
Keywords: syndrome protein; antigen processing; protein regulates; regulates antigen ... See more keywords
Wiskott-Aldrich Syndrome Protein: Roles in Signal Transduction in T Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.674572
Abstract: Signal transduction regulates the proper function of T cells in an immune response. Upon binding to its specific ligand associated with major histocompatibility complex (MHC) molecules on an antigen presenting cell, the T cell receptor… read more here.
Keywords: syndrome protein; aldrich syndrome; signal transduction; wiskott aldrich ... See more keywords
Discovery of a Novel Bloom’s Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232314798
Abstract: Prostate cancer (PCa) is a common cancer and a major cause of cancer-related death worldwide in men, necessitating novel targets for cancer therapy. High expression of Bloom’s syndrome protein (BLM) helicase is associated with the… read more here.
Keywords: prostate cancer; blm; syndrome protein; bloom syndrome ... See more keywords