Engineered exosome for NIR-triggered drug delivery and superior synergistic chemo-phototherapy in a glioma model
Sign Up to like & getrecommendations! Published in 2020 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2020.100723
Abstract: Abstract Most of chemotherapies are less effective when using alone. Exosomes (Exos) are cell derived nanovesicles that can serve as delivery nanoplatforms. Thus, Exos-based synergistic treatment is emerging as a promising strategy. Nevertheless, it is… read more here.
Keywords: synergistic chemo; delivery; chemo phototherapy; glioma model ... See more keywords
Glycosylated BODIPY- Incorporated Pt(II) Metallacycles for Targeted and Synergistic Chemo-Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.2c01940
Abstract: Pt(II)-BODIPY complexes combine the chemotherapeutic activity of Pt(II) with the photocytotoxicity of BODIPYs. Additional conjugation with targeting ligands can boost the uptake by cancer cells that overexpress the corresponding receptors. We describe two Pt(II) triangles,… read more here.
Keywords: metallacycles targeted; incorporated metallacycles; glycosylated bodipy; chemo photodynamic ... See more keywords
Red Blood Cell Membrane Camouflaged Mesoporous Silica Nanorods as Nanocarriers for Synergistic Chemo-photothermal Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "IEEE transactions on nanobioscience"
DOI: 10.1109/tnb.2022.3233378
Abstract: In recent years, nanoparticles camouflaged by red blood cell membrane (RBCM) have become a potential nano-drug delivery platform due to their good biocompatibility and immune evasion capability. Here, a multifunctional drug nanocarrier based on RBCM… read more here.
Keywords: cell; mesoporous silica; membrane; drug ... See more keywords
Lipoparticles for Synergistic Chemo-Photodynamic Therapy to Ovarian Carcinoma Cells: In vitro and in vivo Assessments
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s285950
Abstract: Purpose Lipoparticles are the core-shell type lipid-polymer hybrid systems comprising polymeric nanoparticle core enveloped by single or multiple pegylated lipid layers (shell), thereby melding the biomimetic properties of long-circulating vesicles as well as the mechanical… read more here.
Keywords: microscopy; chemo photodynamic; therapy ovarian; lipoparticles synergistic ... See more keywords
Synergistic chemo-photothermal and ferroptosis therapy of polydopamine nanoparticles for esophageal cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Nanomedicine"
DOI: 10.2217/nnm-2022-0064
Abstract: Aim: To develop synergistic chemo-photothermal and ferroptosis therapy nanoparticles to improve the efficacy of treatment for esophageal cancer. Materials & methods: Fe3O4@PDA-HCPT nanoparticles (NPs) were constructed and characterized. Their synergistic antitumor effects were evaluated in EC1… read more here.
Keywords: photothermal ferroptosis; esophageal cancer; ferroptosis therapy; synergistic chemo ... See more keywords
A pH-Responsive Drug Delivery System Based on Conjugated Polymer for Effective Synergistic Chemo-/Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28010399
Abstract: Stimuli-responsive drug release and photodynamic therapy (PDT) have aroused extensive attention for their enormous potential in antitumor treatment. pH-responsive drug delivery systems (PFE-DOX-1 and PFE-DOX-2) based on water-soluble conjugated polymers were constructed in this work… read more here.
Keywords: responsive drug; therapy; drug delivery; synergistic chemo ... See more keywords
Supramolecular nanomaterials based on hollow mesoporous drug carriers and macrocycle-capped CuS nanogates for synergistic chemo-photothermal therapy
Sign Up to like & getrecommendations! Published in 2020 at "Theranostics"
DOI: 10.7150/thno.40066
Abstract: Multifunctional supramolecular nanoplatforms that integrate the advantages of different therapeutic techniques can trigger multimodal synergistic treatment of tumors, thus representing an emerging powerful tool for cancer therapeutics. Methods: In this work, we design and fabricate… read more here.
Keywords: cus; synergistic chemo; drug; chemo photothermal ... See more keywords