Binary Synergistic Combinations of Lavender and Fennel Essential Oils with Amoxicillin.
Sign Up to like & getrecommendations! Published in 2022 at "Planta medica"
DOI: 10.1055/a-1891-1119
Abstract: Microbial resistance is an important problem in modern healthcare systems. In addition to drug resistance, the side effects of current antibiotic applications are also known issues. In this present study, binary combinations of amoxicillin with… read more here.
Keywords: binary synergistic; essential oils; fennel essential; synergistic combinations ... See more keywords
Synergistic combinations of azoles and antihistamines against Candida species in vitro.
Sign Up to like & getrecommendations! Published in 2018 at "Medical mycology"
DOI: 10.1093/mmy/myy088
Abstract: Fungal infections are a major cause of skin and mucosal membrane disease. Immunocompromised individuals, such as those undergoing chemotherapy, are most susceptible to fungal infections. With a growing population of immunocompromised patients, there are many… read more here.
Keywords: combinations azoles; azoles antihistamines; synergistic combinations; antihistamines candida ... See more keywords
Checkerboard Analysis To Evaluate Synergistic Combinations of Existing Antifungal Drugs and Propylene Glycol Monocaprylate in Isolates from Recalcitrant Tinea Corporis and Cruris Patients Harboring Squalene Epoxidase Gene Mutation
Sign Up to like & getrecommendations! Published in 2021 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00321-21
Abstract: Recalcitrant dermatophytic infections of the glabrous skin (tinea corporis/cruris/faciei) pose a huge challenge to health care systems. Combinations of oral and topical drugs may potentially improve cure rates, but the same has never been objectively… read more here.
Keywords: tinea corporis; recalcitrant tinea; corporis cruris; synergistic combinations ... See more keywords
Synergistic Combinations and Repurposed Antibiotics Active against the Pandrug-Resistant Klebsiella pneumoniae Nevada Strain
Sign Up to like & getrecommendations! Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01374-19
Abstract: In early 2017, the Centers for Disease Control and Prevention issued an alarming report describing a woman in Nevada who died in the setting of infection with a pan-resistant Klebsiella pneumoniae isolate that harbored an… read more here.
Keywords: combinations repurposed; resistant klebsiella; synergistic combinations; klebsiella pneumoniae ... See more keywords
Combination Therapy and the Evolution of Resistance: The Theoretical Merits of Synergism and Antagonism in Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-1201
Abstract: The search for effective combination therapies for cancer has focused heavily on synergistic combinations because they exhibit enhanced therapeutic efficacy at lower doses. Although synergism is intuitively attractive, therapeutic success often depends on whether drug… read more here.
Keywords: combination; evolution; synergistic combinations; drug ... See more keywords
Screening-based approach to discover effective platinum-based chemotherapies for cancers with poor prognosis
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0211268
Abstract: Drug combinations are extensively used to treat cancer and are often selected according to complementary mechanisms. Here, we describe a cell-based high-throughput screening assay for identification of synergistic combinations between broadly applied platinum-based chemotherapeutics and… read more here.
Keywords: platinum; platinum based; synergistic combinations; screening based ... See more keywords
Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.73027
Abstract: The emergence of SARS-CoV-2 variants threatens current vaccines and therapeutic antibodies and urgently demands powerful new therapeutics that can resist viral escape. We therefore generated a large nanobody repertoire to saturate the distinct and highly… read more here.
Keywords: highly synergistic; synergistic combinations; escape; combinations nanobodies ... See more keywords