Phage-Guided Targeting, Discriminated Imaging and Synergistic Killing of Bacteria by AIE Bioconjugates.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b12936
Abstract: New agents with particular specificity toward targeted bacteria and super efficacy in antibacterial activity, are urgently needed in facing the crisis of worldwide antibiotic resistance. Herein, a novel strategy by equipping bacteriophage (PAP) with photodynamic… read more here.
Keywords: imaging synergistic; synergistic killing; phage; guided targeting ... See more keywords
Metabolomics Study of the Synergistic Killing of Polymyxin B in Combination with Amikacin against Polymyxin-Susceptible and -Resistant Pseudomonas aeruginosa
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DOI: 10.1128/aac.01587-19
Abstract: In the present study, we employed untargeted metabolomics to investigate the synergistic killing mechanism of polymyxin B in combination with an aminoglycoside, amikacin, against a polymyxin-susceptible isolate of Pseudomonas aeruginosa, FADDI-PA111 (MIC = 2 mg/liter for… read more here.
Keywords: amikacin polymyxin; combination; polymyxin susceptible; polymyxin ... See more keywords
Proteomics Study of the Synergistic Killing of Tigecycline in Combination With Aminoglycosides Against Carbapenem-Resistant Klebsiella pneumoniae
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DOI: 10.3389/fcimb.2022.920761
Abstract: Co-administration of antibiotics with synergistic effects is one method to combat carbapenem-resistant organisms. Although the synergistic effects of tigecycline combined with aminoglycosides against carbapenem-resistant Klebsiella pneumoniae (CRKP) have been demonstrated in vitro and in animal… read more here.
Keywords: carbapenem resistant; klebsiella pneumoniae; synergistic killing; combination ... See more keywords