SYNFRIZZ: A first-in-human (FIH) study of a radiolabeled monoclonal antibody (Mab) targeting frizzled homolog 10 (FZD10) in patients (pts) with advanced synovial sarcomas (SyS).
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DOI: 10.1200/jco.2017.35.15_suppl.11054
Abstract: 11054Background: Advanced SyS are rare tumors with limited curative options. FZD10 is highly expressed in SyS but not in normal adult tissue. OTSA101 is a MAb targeting FZD10, labelled with a radio... read more here.
Keywords: synfrizz first; fzd10; sys; mab targeting ... See more keywords