Epigenetic modulation rescues neurodevelopmental deficits in Syngap1+/− mice
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DOI: 10.1111/acel.14408
Abstract: SYNGAP1 is a Ras GTPase‐activating protein that plays a crucial role during brain development and in synaptic plasticity. Sporadic heterozygous mutations in SYNGAP1 affect social and emotional behaviour observed in intellectual disability (ID) and autism… read more here.
Keywords: p300 cbp; csp ttk21; syngap1; syngap1 mice ... See more keywords