SynNotch-Programmed Macrophages for Cancerous Cell Detection and Sensing.
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DOI: 10.1021/acssensors.4c01997
Abstract: Synthetic Notch (synNotch) receptors have enabled mammalian cells to sense extracellular ligands and respond by activating user-prescribed transcriptional programs. Based on the synNotch system, we describe a cell-based in vivo sensor for cancerous cell detection.… read more here.
Keywords: cancer; synnotch; cell; synnotch programmed ... See more keywords