Synonymous ADAMTS13 variants impact molecular characteristics and contribute to variability in active protein abundance
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DOI: 10.1182/bloodadvances.2022007065
Abstract: Key Points ADAMTS13 sSNVs affect mRNA thermodynamic stability and may disturb mRNA-splicing sites. Synonymous variations may affect ADAMTS13 function and contribute to large variability in protein expression levels in healthy individuals. read more here.
Keywords: synonymous adamts13; variants impact; variability; adamts13 variants ... See more keywords