Pharmacokinetics of betamethasone in plasma, urine, and synovial fluid following intra-articular administration to exercised thoroughbred horses.
Sign Up to like & getrecommendations! Published in 2017 at "Drug testing and analysis"
DOI: 10.1002/dta.2170
Abstract: The use of corticosteroids, such as betamethasone, in performance horses is tightly regulated. The objective of the current study was to describe the plasma pharmacokinetics of betamethasone as well as time-related urine and synovial fluid… read more here.
Keywords: urine synovial; betamethasone; articular administration; synovial fluid ... See more keywords
A Quantitative PCR Screening Method for Adeno-Associated Viral Vector 2-mediated Gene Doping.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3152
Abstract: Gene therapy is currently prohibited in human and equine athletes and novel analytical methods are needed for its detection. Most in vivo products use non-integrating, recombinant viral vectors derived from adeno-associated virus (AAV) to deliver… read more here.
Keywords: quantitative pcr; gene doping; raav; adeno associated ... See more keywords
Neutrophil recruitment to inflamed joints can occur without cellular priming
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ab0918-369r
Abstract: Recruitment of neutrophils from blood to tissues is a cardinal event in inflammation during which neutrophils switch from a resting, naive state to a preactivated, primed phenotype; the priming process is characterized by alterations in… read more here.
Keywords: cellular priming; blood; inflamed joints; recruitment ... See more keywords
Lipid profile of human synovial fluid following intra‐articular ankle fracture
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23217
Abstract: This study characterizes the metabolic profile of synovial fluid after intra‐articular ankle fracture with an emphasis on changes in the lipid profile. Bilateral ankle synovial fluid from 19 patients with unilateral intra‐articular ankle fracture was… read more here.
Keywords: ankle; fracture; fluid; fatty acids ... See more keywords
Identification and quantification of degradome components in human synovial fluid reveals an increased proteolytic activity in knee osteoarthritis patients vs controls.
Sign Up to like & getrecommendations! Published in 2023 at "Proteomics"
DOI: 10.1002/pmic.202300040
Abstract: Synovial fluid (SF) may contain cleavage products of proteolytic activities. Our aim was to characterize the degradome through analysis of proteolytic activity and differential abundance of these components in a peptidomic analysis of SF in… read more here.
Keywords: osteoarthritis patients; knee osteoarthritis; activity; knee ... See more keywords
Synovial Fluid Mediated Aggregation of Clinical Strains of Four Enterobacterial Species.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2020_573
Abstract: Septic arthritis and prosthetic joint infection (PJI) are conditions commonly associated with Gram-positive cocci, however, a drastic increase in cases derived from enterobacterial species has been observed. Recently it has been reported by multiple groups… read more here.
Keywords: fluid; mediated aggregation; synovial fluid; fluid mediated ... See more keywords
Thick and yellowish articular effusion: a challenging diagnosis! Focus on cholesterol crystal deposition in joint
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation Research"
DOI: 10.1007/s00011-020-01369-3
Abstract: We reported a case of an 84-year-old woman with an old inability to actively elevate her left upper limb, with recent shoulder pain. X-ray showed an important arthropathy of the left gleno-humeral joint with epiphyseal… read more here.
Keywords: thick yellowish; joint; cholesterol; deposition ... See more keywords
Multiplex PCR Unyvero i60 ITI application improves detection of low-virulent microorganisms in periprosthetic joint infections
Sign Up to like & getrecommendations! Published in 2018 at "International Orthopaedics"
DOI: 10.1007/s00264-018-4136-z
Abstract: PurposeThe aim of this study was to evaluate the pre-operative performance of an automated multiplex PCR (mPCR) system in patients with suspected periprosthetic joint infection (PJI).MethodsUnder sterile conditions, synovial fluid samples from patients with a… read more here.
Keywords: mpcr; detection; synovial fluid; multiplex pcr ... See more keywords
Synovial fluid analysis with leukocyte esterase reagent strip test
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-05608-8
Abstract: To determine whether leukocyte esterase reagent strip test (LERST) analysis could help distinguish inflammatory arthritis from mechanical joint effusion. We analyzed synovial fluid (SF) from consecutive patients with a non-traumatic joint effusion during a 6-month… read more here.
Keywords: analysis; synovial fluid; leukocyte esterase; reagent strip ... See more keywords
Pathogen or contaminant? Distinguishing true infection from synovial fluid culture contamination in patients with suspected septic arthritis
Sign Up to like & getrecommendations! Published in 2017 at "Infection"
DOI: 10.1007/s15010-017-1051-y
Abstract: BackgroundIsolation of bacteria from synovial fluid (SF) is the gold standard for diagnosis of septic arthritis (SA). Contamination results in misdiagnosis and mismanagement. This study identifies clinical characteristics, microbiology, and outcomes of patients with contaminated… read more here.
Keywords: septic arthritis; patients suspected; contamination; synovial fluid ... See more keywords
Preoperative synovial fluid culture poorly predicts the pathogen causing periprosthetic joint infection
Sign Up to like & getrecommendations! Published in 2020 at "Infection"
DOI: 10.1007/s15010-020-01540-2
Abstract: We investigated the value of preoperative pathogen detection and evaluated its concordance with intraoperative cultures in patients with culture-positive periprosthetic joint infection (PJI). Culture-positive PJI episodes with available preoperative (synovial fluid) and intraoperative cultures (periprosthetic… read more here.
Keywords: pathogen; preoperative synovial; synovial fluid; culture ... See more keywords