Synovial Fluid-derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP-1 Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202514220
Abstract: Traditionally considered a sterile environment, the articular cavity has this perception overturned with advances in multi-omics technologies-microbial communities are increasingly identified in once-thought sterile tissues, making the articular cavity a potential microbial niche. However, the… read more here.
Keywords: micrococcus luteus; progression; luteus g18; synovial fluid ... See more keywords
Pharmacokinetics of betamethasone in plasma, urine, and synovial fluid following intra-articular administration to exercised thoroughbred horses.
Sign Up to like & getrecommendations! Published in 2017 at "Drug testing and analysis"
DOI: 10.1002/dta.2170
Abstract: The use of corticosteroids, such as betamethasone, in performance horses is tightly regulated. The objective of the current study was to describe the plasma pharmacokinetics of betamethasone as well as time-related urine and synovial fluid… read more here.
Keywords: urine synovial; betamethasone; articular administration; synovial fluid ... See more keywords
A Quantitative PCR Screening Method for Adeno-Associated Viral Vector 2-mediated Gene Doping.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3152
Abstract: Gene therapy is currently prohibited in human and equine athletes and novel analytical methods are needed for its detection. Most in vivo products use non-integrating, recombinant viral vectors derived from adeno-associated virus (AAV) to deliver… read more here.
Keywords: quantitative pcr; gene doping; raav; adeno associated ... See more keywords
Synovial fluid research based on SERS and SERRS for enhanced detection of biomarkers in staged osteoarthritis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202400024
Abstract: Surface‐enhanced (resonance) Raman scattering (SER(R)S) can extremely enhance Raman intensity of samples, which is helpful for detecting synovial fluid (SF) that does not show Raman activity under normal conditions. In this study, SER(R)S spectra of… read more here.
Keywords: based sers; fluid research; research based; synovial fluid ... See more keywords
Noncontact Diffuse Reflectance Spectroscopy of Synovial Fluid Samples for Rapid Identification of Infections
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DOI: 10.1002/jbio.202400213
Abstract: Severe joint infections, such as septic arthritis, require rapid diagnostic testing of the synovial fluid aspirated from joints level so that a surgical team can be assembled quickly. We present a diffuse reflectance spectroscopy (DRS)… read more here.
Keywords: spectroscopy; diffuse reflectance; synovial fluid; reflectance spectroscopy ... See more keywords
Neutrophil recruitment to inflamed joints can occur without cellular priming
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ab0918-369r
Abstract: Recruitment of neutrophils from blood to tissues is a cardinal event in inflammation during which neutrophils switch from a resting, naive state to a preactivated, primed phenotype; the priming process is characterized by alterations in… read more here.
Keywords: cellular priming; blood; inflamed joints; recruitment ... See more keywords
Lipid profile of human synovial fluid following intra‐articular ankle fracture
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23217
Abstract: This study characterizes the metabolic profile of synovial fluid after intra‐articular ankle fracture with an emphasis on changes in the lipid profile. Bilateral ankle synovial fluid from 19 patients with unilateral intra‐articular ankle fracture was… read more here.
Keywords: ankle; fracture; fluid; fatty acids ... See more keywords
Synovial fluid dual‐biomarker algorithm accurately differentiates osteoarthritis from inflammatory arthritis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.26005
Abstract: Osteoarthritis (OA) prevalence increases as the population ages. Diagnosing osteoarthritis often occurs in the late stages when cartilage degradation is severe, making it difficult to distinguish from other types of arthritis. Accurate differentiation of primary… read more here.
Keywords: inflammatory arthritis; osteoarthritis inflammatory; synovial fluid; biomarker ... See more keywords
Identification and quantification of degradome components in human synovial fluid reveals an increased proteolytic activity in knee osteoarthritis patients vs controls.
Sign Up to like & getrecommendations! Published in 2023 at "Proteomics"
DOI: 10.1002/pmic.202300040
Abstract: Synovial fluid (SF) may contain cleavage products of proteolytic activities. Our aim was to characterize the degradome through analysis of proteolytic activity and differential abundance of these components in a peptidomic analysis of SF in… read more here.
Keywords: osteoarthritis patients; knee osteoarthritis; activity; knee ... See more keywords
Synovial Fluid Mediated Aggregation of Clinical Strains of Four Enterobacterial Species.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2020_573
Abstract: Septic arthritis and prosthetic joint infection (PJI) are conditions commonly associated with Gram-positive cocci, however, a drastic increase in cases derived from enterobacterial species has been observed. Recently it has been reported by multiple groups… read more here.
Keywords: fluid; mediated aggregation; synovial fluid; fluid mediated ... See more keywords
Thick and yellowish articular effusion: a challenging diagnosis! Focus on cholesterol crystal deposition in joint
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation Research"
DOI: 10.1007/s00011-020-01369-3
Abstract: We reported a case of an 84-year-old woman with an old inability to actively elevate her left upper limb, with recent shoulder pain. X-ray showed an important arthropathy of the left gleno-humeral joint with epiphyseal… read more here.
Keywords: thick yellowish; joint; cholesterol; deposition ... See more keywords