Nanomedicines Reprogram Synovial Macrophages by Scavenging Nitric Oxide and Silencing CA9 in Progressive Osteoarthritis
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202207490
Abstract: Osteoarthritis (OA) is a progressive joint disease characterized by inflammation and cartilage destruction, and its progression is closely related to imbalances in the M1/M2 synovial macrophages. A two‐pronged strategy for the regulation of intracellular/extracellular nitric… read more here.
Keywords: reprogram synovial; scavenging nitric; nitric oxide; synovial macrophages ... See more keywords
Joint synovial macrophages as a potential target for intra-articular treatment of osteoarthritis-related pain.
Sign Up to like & getrecommendations! Published in 2021 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2021.11.014
Abstract: Osteoarthritis is the most common form of joint disease and is one of the leading causes of chronic pain. Given the multi-factorial nature, numerous efforts have been made to clarify the multiple factors impacting the… read more here.
Keywords: osteoarthritis; synovial macrophages; articular treatment; pain ... See more keywords
AB0227 Transcriptional profiling of synovial macrophages using minimally invasive ultrasound-guided synovial biopsies in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.7594
Abstract: Background Despite the many therapies for patients with rheumatoid arthritis (RA), there is little information to guide selection of the most effective treatment for an individual patient. Forty-sixty percent of patients with RA respond (defined… read more here.
Keywords: response; synovial tissue; tissue; rheumatoid arthritis ... See more keywords
Crosstalk between synovial macrophages and fibroblasts in rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2023 at "Histology and histopathology"
DOI: 10.14670/hh-18-628
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease associated with chronic inflammation of joints. Abnormally activated cells such as synovial macrophages and synovial fibroblasts induce RA pathogenesis and ultimately joint destruction. Since macrophages can change their… read more here.
Keywords: synovial macrophages; crosstalk synovial; macrophages fibroblasts; rheumatoid arthritis ... See more keywords
Immunoregulation of synovial macrophages for the treatment of osteoarthritis
Sign Up to like & getrecommendations! Published in 2023 at "Open Life Sciences"
DOI: 10.1515/biol-2022-0567
Abstract: Abstract Osteoarthritis (OA) is the most common joint disease affecting approximately 10% of men and 18% of women older than 60. Its pathogenesis is still not fully understood; however, emerging evidence has suggested that chronic… read more here.
Keywords: treatment osteoarthritis; macrophages treatment; immunoregulation synovial; synovial macrophages ... See more keywords
Ontogeny of Synovial Macrophages and the Roles of Synovial Macrophages From Different Origins in Arthritis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01146
Abstract: The ontogeny of macrophages in most organ/tissues in human body has been proven. Due to the limited number and inaccessibility of synovial macrophages (SM), the origin of SM has not been fully illuminated. The objective… read more here.
Keywords: different origins; ontogeny synovial; esm bmsm; synovial macrophages ... See more keywords