Synovial membrane mesenchymal stem cells for cartilaginous tissues repair
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology Reports"
DOI: 10.1007/s11033-021-07051-z
Abstract: Background The present review is focused on general aspects of the synovial membrane as well as specialized aspects of its cellular constituents, particularly the composition and location of synovial membrane mesenchymal stem cells (S-MSCs). S-MSC… read more here.
Keywords: membrane; synovial membrane; stem cells; membrane mesenchymal ... See more keywords
Conditioned medium of IGF1-induced synovial membrane mesenchymal stem cells increases chondrogenic and chondroprotective markers in chondrocyte inflammation
Sign Up to like & getrecommendations! Published in 2021 at "Bioscience Reports"
DOI: 10.1042/bsr20202038
Abstract: Abstract Recently, mesenchymal stem cells (MSCs) have been the most explored cells for cell therapy for osteoarthritis (OA) that can be obtained from various sources. Synovial membrane MSCs (SMMSCs) provide best potential for OA therapy,… read more here.
Keywords: growth; synovial membrane; mesenchymal stem; stem cells ... See more keywords
High in vivo levels of adipsin lead to increased knee tissue degradation in osteoarthritis: data from humans and animal models
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DOI: 10.1093/rheumatology/key181
Abstract: Objective This study explored the role of the adipokine adipsin in OA. Methods Control and OA articular tissues, cells and serum were obtained from human individuals. Serum adipsin levels of human OA individuals were compared… read more here.
Keywords: adipsin levels; synovial membrane; serum; adipsin ... See more keywords
AB0797 THE ROLE OF ULTRASOUND CRITERIA IN ASSESSING PAIN SYNDROME IN THE KNEE JOINT IN PATIENTS WITH RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.3224
Abstract: Pain syndrome and pathological changes in the synovium detected by ultrasound can be early signs of various diseases of the joints [1].the use of ultrasound criteria for changes in the synovial membrane of the joint… read more here.
Keywords: knee joint; pain; synovial membrane; vascularization ... See more keywords
Production of Cytotoxic Antibodies After Intra-Articular Injection of Allogeneic Synovial Membrane Mesenchymal Stem Cells With and Without LPS Administration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.871216
Abstract: Allogeneic mesenchymal stem cells (MSC) are widely used in clinical routine due to the shorter expansion time and reliability of its quality. However, some recipients can produce alloantibodies that recognize MSCs and activate the immune… read more here.
Keywords: injection; intra articular; production; allo ... See more keywords
The synovial fluid fibroblast-like synoviocyte: A long-neglected piece in the puzzle of rheumatoid arthritis pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.942417
Abstract: Rheumatoid arthritis (RA) is a systemic autoimmune disease during which fibroblast-like synoviocytes (FLS) contribute to both joint inflammation and destruction. FLS represent the core component of the synovial membrane. Following inflammation of this membrane, an… read more here.
Keywords: rheumatoid arthritis; fibroblast like; membrane; synovial membrane ... See more keywords
The forgotten key players in rheumatoid arthritis: IL-8 and IL-17 – Unmet needs and therapeutic perspectives
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.956127
Abstract: Despite the relevant advances in our understanding of the pathogenetic mechanisms regulating inflammation in rheumatoid arthritis (RA) and the development of effective therapeutics, to date, there is still a proportion of patients with RA who… read more here.
Keywords: forgotten key; extra articular; rheumatoid arthritis; synovial membrane ... See more keywords
The Role of Synovial Membrane in the Development of a Potential In Vitro Model of Osteoarthritis
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DOI: 10.3390/ijms23052475
Abstract: There is a lack of in vitro models able to plausibly represent the inflammation microenvironment of knee osteoarthritis (OA). We analyzed the molecules released from OA tissues (synovial membrane, cartilage, infrapatellar fat pad) and investigated… read more here.
Keywords: synovial membrane; vitro model; osteoarthritis; membrane ... See more keywords
Increased NMUR1 Expression in Mast Cells in the Synovial Membrane of Obese Osteoarthritis Patients
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911237
Abstract: Obesity is a risk factor for knee osteoarthritis (KOA). Neuromedin U (NMU) and NMU receptors (NMUR1 and NMUR2) are associated with obesity-related disorders and found in mast cells (MCs), which are elevated in osteoarthritis. However,… read more here.
Keywords: osteoarthritis patients; osteoarthritis; expression; mast cells ... See more keywords