A Citrate Synthase Splice Variant Rewires the TCA Cycle to Promote Colorectal Cancer Progression
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/0008-5472.can-24-2355
Abstract: The citrate synthase variant CS-ΔEx4 augments TCA metabolic flux to facilitate epigenetic reprogramming and colorectal carcinogenesis and can be targeted with a small molecule, providing a promising treatment strategy for colorectal cancer. read more here.
Keywords: colorectal cancer; cancer; synthase splice; citrate synthase ... See more keywords