Pyrimidine Nucleosides Syntheses by Late-Stage Base Heterocyclization Reactions
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DOI: 10.1021/acs.orglett.2c03152
Abstract: An efficient two-step procedure for the syntheses of pyrimidine nucleosides is presented. A series of glycosyl 5-(aminomethylene)-1,3-dioxane-4,6-dione derivatives were prepared from β-anomeric isonitriles by reaction with Meldrum’s acid or by allowing aminomethylene Meldrum’s acid to… read more here.
Keywords: stage base; late stage; base heterocyclization; nucleosides syntheses ... See more keywords