Syntheses of the marine alkaloids 6-oxofascaplysin, fascaplysin and their derivatives
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DOI: 10.1016/j.tetlet.2018.01.023
Abstract: Abstract A simple approach towards the pyrido[1,2-a:3,4-b′]diindole system via the reaction of indigo with methylene active compounds was used for the syntheses of the marine alkaloids 6-oxofascaplysin, fascaplysin, and their derivatives. It was also demonstrated… read more here.
Keywords: fascaplysin derivatives; oxofascaplysin fascaplysin; marine alkaloids; alkaloids oxofascaplysin ... See more keywords
Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses
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DOI: 10.3390/molecules25133049
Abstract: This review considers the results of recent studies on marine excitatory amino acids, including kainic acid, domoic acid, dysiherbaine, and neodysiherbaine A, known as potent agonists of one of subtypes of glutamate receptors, the so-called… read more here.
Keywords: amino acids; marine excitatory; acids structure; excitatory amino ... See more keywords
Concise Syntheses of Marine (Bis)indole Alkaloids Meridianin C, D, F, and G and Scalaridine A via One-Pot Masuda Borylation-Suzuki Coupling Sequence
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DOI: 10.3390/molecules27072233
Abstract: N-Protected 3-iodoindoles were reacted with (di)azine halides in a sequentially Pd-catalyzed one-pot fashion, i.e., by Masuda borylation–Suzuki coupling (MBSC) sequence. This methodology was successfully applied to the concise syntheses of marine indole alkaloids meridianin C,… read more here.
Keywords: suzuki coupling; syntheses marine; one pot; masuda borylation ... See more keywords