Stereoselective Syntheses of Masked β-Amino Acid Containing Phthalides
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DOI: 10.1002/hlca.202200110
Abstract: We herein report a protocol for the asymmetric aldol-initiated cascade addition of isoxazolidin-5-ones to ortho-cyanobenzaldehydes by using Takemoto’s bifunctional organocatalyst. This approach allows for the synthesis of various novel β2,2-amino acid-phthalide conjugates with good enantio-… read more here.
Keywords: acid containing; masked amino; syntheses masked; acid ... See more keywords