Enantioselective synthesis of acyclic monohydrosilanes by steric hindrance assisted C-H silylation.
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DOI: 10.1039/d2cc02307e
Abstract: Herein, a rhodium-catalyzed desymmetrization of dihydrosilanes with heterocyclic compounds via intermolecular dehydrogenative C-H silylation is developed. The strategy tolerates a variety of thianaphthene and thiophene derivatives, giving rise to a wide range of silicon-stereogenic acyclic… read more here.
Keywords: silylation; enantioselective synthesis; monohydrosilanes steric; synthesis acyclic ... See more keywords
Atom and step economical synthesis of acyclic quaternary centers via iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes
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DOI: 10.1039/d2sc02790a
Abstract: Quaternary benzylic centers are accessed with high atom and step economy by Ir-catalyzed alkene hydroarylation. These studies provide unique examples of the use of non-polarized 1,1-disubstituted alkenes in branch selective Murai-type hydro(hetero)arylations. Detailed mechanistic studies… read more here.
Keywords: atom step; step; economical synthesis; synthesis acyclic ... See more keywords