Total synthesis of (-)-akaol A via a conformational constraint strategy
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DOI: 10.1039/c8qo00375k
Abstract: The enantioselective total synthesis of (−)-akaol A has been achieved. The key reaction features a well-designed Friedel–Crafts cyclization, which ensured a cis-fused B/C ring through a conformational constraint strategy. In marked control to trans-fused B/C… read more here.
Keywords: total synthesis; constraint strategy; conformational constraint; synthesis akaol ... See more keywords