Lipase‐catalyzed hydrazine insertion for the synthesis of N′‐alkyl benzohydrazides
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2335
Abstract: N′‐alkyl benzohydrazides are classic organic compounds that have been widely utilized in organic chemistry. In this study, an efficient method was developed for the synthesis of N′‐alkyl benzohydrazides by hydrazine insertion catalyzed by lipase. Under… read more here.
Keywords: alkyl benzohydrazides; chemistry; synthesis alkyl; lipase ... See more keywords
An efficient synthesis of O- and N- alkyl derivatives of 4-aminobenzoic acid and evaluation of their anticancer properties.
Sign Up to like & getrecommendations! Published in 2023 at "Natural product research"
DOI: 10.1080/14786419.2023.2169916
Abstract: A series of twenty alkyl derivatives (2-21) of 4-amino benzoic acid (1, PABA) have been prepared using potassium carbonate and opportune alkylating agents under simple and mild reaction conditions. Compounds (16-21) are reported for the… read more here.
Keywords: derivatives aminobenzoic; alkyl derivatives; synthesis alkyl; efficient synthesis ... See more keywords
Catalytic Synthesis of Alkyl-α,ω-diyl Dimethyl Dicarbonate via Transesterification by Solid Base
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DOI: 10.1246/cl.180460
Abstract: The catalytic synthesis of alkyl-α,ω-diyl dimethyl dicarbonate was achieved firstly by solid base via transesterification of aliphatic diols with dimethyl carbonate under atmospheric pressure. The ... read more here.
Keywords: alkyl diyl; dimethyl dicarbonate; diyl dimethyl; catalytic synthesis ... See more keywords
Facile synthesis of 7-alkyl-1,2,3,4-tetrahydro-1,8-naphthyridines as arginine mimetics using a Horner–Wadsworth–Emmons-based approach
Sign Up to like & getrecommendations! Published in 2020 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.16.134
Abstract: Integrin inhibitors based on the tripeptide sequence Arg–Gly–Asp (RGD) are potential therapeutics for the treatment of idiopathic pulmonary fibrosis (IPF). Herein, we describe an expeditious three-step synthetic sequence of Horner–Wadsworth–Emmons olefination, diimide reduction, and global… read more here.
Keywords: synthesis alkyl; wadsworth emmons; facile synthesis; horner wadsworth ... See more keywords