Sustainable synthesis of ambrisentan – syringic acid cocrystal: employing mechanochemistry in the development of novel pharmaceutical solid form
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DOI: 10.1039/c9ce01818b
Abstract: The present work focuses on the development of a pharmaceutical cocrystal of ambrisentan (AMT), with low aqueous solubility, which can be used to treat pulmonary arterial hypertension. In this regard, a novel cocrystal of AMT… read more here.
Keywords: syringic acid; sustainable synthesis; development; mechanochemistry ... See more keywords