Direct Synthesis of Amides from Nitro Compounds and Alcohols via Borrowing Hydrogenation∇.
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DOI: 10.1021/acs.orglett.5c00600
Abstract: Herein, we report a RuH2(CO)(PPh3)3 catalyzed direct amidation of alcohols using readily available nitro compounds via a catalytic borrowing hydrogen method. This reaction proceeded via cascade reactions, including oxidation of alcohol, reduction of nitro group… read more here.
Keywords: direct synthesis; nitro compounds; alcohols via; compounds alcohols ... See more keywords
Rhodium-Catalyzed Synthesis of Amides from Functionalized Blocked Isocyanates
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DOI: 10.1021/acscatal.9b02641
Abstract: Isocyanates are useful building blocks for the synthesis of amides, although their widespread use has been limited by their high reactivity, which often results in poor functional group tolerance and a propensity to oligomerize. Herein,… read more here.
Keywords: synthesis; rhodium catalyzed; amides functionalized; functionalized blocked ... See more keywords
Electrochemical anion pool synthesis of amides with concurrent benzyl ester synthesis
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DOI: 10.1039/c9gc00707e
Abstract: An atom economic, electrochemical, concurrent synthesis of amides and benzoic esters. read more here.
Keywords: synthesis; synthesis amides; amides concurrent; anion pool ... See more keywords
DIPEA-induced activation of OH− for the synthesis of amides via photocatalysis
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DOI: 10.1039/d2ra02107b
Abstract: The development of green protocols for photocatalysis where water acts as a nucleophile, induced by a weak organic base, is difficult to achieve in organic chemistry. Herein, an efficient light-mediated strategy for the synthesis of… read more here.
Keywords: dipea induced; synthesis amides; photocatalysis; activation synthesis ... See more keywords
Facile synthesis of amides via acceptorless dehydrogenative coupling of aryl epoxides and amines
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DOI: 10.1039/d2sc01959k
Abstract: The synthesis of amides is significant in a wide variety of academic and industrial fields. We report here a new reaction, namely acceptorless dehydrogenative coupling of epoxides and amines to form amides catalyzed by ruthenium… read more here.
Keywords: aryl epoxides; synthesis amides; epoxides amines; dehydrogenative coupling ... See more keywords
KOH-Mediated Synthesis of Amides from Azides and 1,3-Dicarbonyl Compounds
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DOI: 10.1039/d3nj05813a
Abstract: A simple method for the preparation of N-phenylbenzamides from azidobenzenes and 1,3-diphenylpropane-1,3-diones is described. In the reaction, N-phenylbenzamides were generated by [3+2] cycloaddition and intramolecular ring opening. The products were... read more here.
Keywords: dicarbonyl compounds; koh mediated; azides dicarbonyl; mediated synthesis ... See more keywords
Efficient synthesis of amides from secondary alcohols and CH3CN promoted by Fe(NO3)3·9H2O
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DOI: 10.1039/d4ra04146a
Abstract: The Ritter reaction is the most attractive method for synthesizing amides, and various acids have been used to promote this reaction. Compared to these acids, Fe(NO3)3·9H2O is less toxic and costly, and it shows relatively… read more here.
Keywords: synthesis amides; synthesis; no3 9h2o; secondary alcohols ... See more keywords
Synthesis of amides via TBN-induced oxidation cross-coupling of acetonitrile and N-sulfinylanilines
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DOI: 10.1080/00397911.2025.2494245
Abstract: Abstract A novel method for the synthesis of amides has been developed that features – tert-butyl nitrite-induced oxidative cross-coupling of acetonitrile with N-sulfinylanilines. Acetonitrile serves as the C2 building block in this process. The present… read more here.
Keywords: acetonitrile sulfinylanilines; cross coupling; synthesis amides; synthesis ... See more keywords
One-pot synthesis of amides from aryloyl peroxides and aldimines in dimethyl sulfoxide
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DOI: 10.1080/00397911.2025.2508211
Abstract: Abstract A novel method for amide synthesis from aldimines using an aryloyl peroxide/DMSO system has been developed. The acyl groups of the resulting amides are derived from the aryloyl peroxide, while the N-containing motifs originate… read more here.
Keywords: synthesis amides; one pot; synthesis; aryloyl peroxide ... See more keywords
The Synthesis of Amides through Direct Amination of Aldehydes with Amines
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DOI: 10.2174/1385272823666190614114457
Abstract: Amide bonds are amongst the most fundamental groups in organic synthesis, and they are widely found in natural products, pharmaceuticals and material science. Over the past decade, methods for the direct amination of aldehydes have… read more here.
Keywords: synthesis amides; amination aldehydes; direct amination; amides direct ... See more keywords
Microwave-Assisted Catalytic Method for a Green Synthesis of Amides Directly from Amines and Carboxylic Acids
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DOI: 10.3390/molecules25081761
Abstract: Amide bonds are among the most interesting and abundant molecules of life and products of the chemical pharmaceutical industry. In this work, we describe a method of the direct synthesis of amides from carboxylic acids… read more here.
Keywords: carboxylic acids; method; microwave assisted; assisted catalytic ... See more keywords