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Published in 2020 at "Fitoterapia"
DOI: 10.1016/j.fitote.2020.104533
Abstract: An efficient, microwave-assisted, oxidant-interceded, transition-metal-free, cross-dehydrogenative Csp2-Csp3 coupling of C8-Caffeine 2/Theobromine 3/theophylline 4 with substituted aliphatic alcohols 11a-l via CH bond activation for the preparation of series of substituted C8-(hydroxymethyl) Caffeine 12a-l/theobromine 13a-c/theophylline 14a-b has…
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Keywords:
modified synthesis;
synthesis analogues;
analogues naturally;
microwave assisted ... See more keywords
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Published in 2022 at "Journal of Chemical Research"
DOI: 10.1177/17475198211047209
Abstract: The preparation of six new optically active analogues of the natural product febrifugine (1) is reported. These analogues, lacking the hydroxy group from the natural product, were prepared from optically active N-protected S-pelletierine (7) and…
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Keywords:
stereoselective synthesis;
analogues deoxyfebrifugine;
synthesis analogues;