Articles with "synthesis antikinetoplastid" as a keyword



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Synthesis and antikinetoplastid evaluation of bis(benzyl)spermidine derivatives.

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Published in 2018 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2018.02.087

Abstract: This study describes the synthesis and the biological evaluation of twenty-four original bis(benzyl)spermidines. Structural modifications of the polyamine scaffold were performed in order to avoid easily metabolized bonds. Some bis(benzyl)polyamine derivatives have demonstrated promising activity… read more here.

Keywords: synthesis antikinetoplastid; bis benzyl; antikinetoplastid evaluation; evaluation ... See more keywords