Synthesis and antimicrobial testing of 5-fluorouracil derivatives.
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DOI: 10.1002/ardp.202300103
Abstract: Antibiotic resistance has increased the demand for novel treatments against multidrug-resistant microorganisms. In the research literature, 5-fluorouracil (5-FU) was proposed as an alternative due to its intrinsic antibacterial property. However, given its toxicity profile at… read more here.
Keywords: fluorouracil derivatives; testing fluorouracil; antimicrobial testing; synthesis antimicrobial ... See more keywords
Synthesis and antimicrobial evaluation of piperic acid amides and their lower homologues
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DOI: 10.1002/ddr.21630
Abstract: Seven piperic acid amides along with their lower homologs (12) were synthesized using HATU‐DIPEA coupling reagent. All the synthesized derivatives were evaluated for their antibacterial activities against Staphylococcus aureus, Pseudomonas aeruginosa, and vancomycin‐resistant P. aeruginosa.… read more here.
Keywords: acid amides; piperic acid; found active; synthesis antimicrobial ... See more keywords
Synthesis and Antimicrobial Activity of 1,3,4‐Oxadiazole‐2(3H)‐thione and Azidomethanone Derivatives Based on Quinoline‐4‐carbohydrazide Derivatives
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DOI: 10.1002/jhet.2529
Abstract: A new series compounds of quinoline derivatives were synthesized by reaction of 3-(carboxymethyl)-2-arylquinoline-4-carboxylic acids 1a, 1b, 1c with different nucleophiles. The structures of the new compounds were elucidated on the basis of FTIR, 1H-NMR, 13C-NMR… read more here.
Keywords: antimicrobial activity; oxadiazole thione; activity oxadiazole; synthesis antimicrobial ... See more keywords
Synthesis and Antimicrobial Evaluations of New 5-aryl Linked Bispyrazolines
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DOI: 10.1002/jhet.2583
Abstract: Syntheses of new bispyrazolines 4a, 4b, 4c, 4d, 4e, 4f, 4g built around the aliphatic linkers of varying lengths have been described. The intermediate bischalcones and final bishetrocyclics were also evaluated for their antimicrobial activities. read more here.
Keywords: aryl linked; new aryl; antimicrobial evaluations; synthesis antimicrobial ... See more keywords
Synthesis and Antimicrobial Activity of Azolyl Pyrimidines
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DOI: 10.1002/jhet.2615
Abstract: A new class of azolyl pyrimidines linked by diamino sulfone moiety was prepared and studied their antimicrobial activity. Chloro-substituted and nitro-substituted thiazolyl pyrimidines (9c and 9e) showed excellent antibacterial activity against Bacillus subtilis, while imidazolyl… read more here.
Keywords: antimicrobial activity; azolyl pyrimidines; synthesis antimicrobial; activity azolyl ... See more keywords
Synthesis and Antimicrobial Activity of Some Novel Quinoline, Chromene, Pyrazole Derivatives Bearing Triazolopyrimidine Moiety
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DOI: 10.1002/jhet.2645
Abstract: 7-Amino-3-phenyl-[1,2,4]triazolo [4,3-a] pyrimidin-5(1H)-one () was utilized as key intermediate for the synthesis of some new, quinolines and , acrylonitrile and , coumarin , and pyrazoles incorporating triazolopyrimidines. The structures of the newly synthesized compounds were… read more here.
Keywords: activity novel; antimicrobial activity; novel quinoline; quinoline chromene ... See more keywords
Synthesis and Antimicrobial Activity of Some New 3,4‐Disubstituted Pyrroles and Pyrazoles
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DOI: 10.1002/jhet.3012
Abstract: A variety of 3,4-disubstituted pyrroles and pyrazoles were synthesized by the treatment of 1,3-dipolar reagents viz., tosylmethyl isocyanide, and diazomethane to heteroaryl chalcones and evaluated for their antimicrobial activity. Among all the tested compounds, 14b… read more here.
Keywords: activity new; disubstituted pyrroles; antimicrobial activity; synthesis antimicrobial ... See more keywords
Microwave Assisted Synthesis and Antimicrobial Potential of Quinoline-Based 4-Hydrazide-Hydrazone Derivatives
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DOI: 10.1002/jhet.3050
Abstract: The World Academy of Sciences (TWAS) was gratefully acknowledged by OOA for the sponsorship of this present work under the TWAS Research Grant for Individual Scientists in Basic Sciences Programme (grant no.: 14-069 RG/CHE/AF/AC_1). read more here.
Keywords: antimicrobial potential; microwave assisted; synthesis antimicrobial; assisted synthesis ... See more keywords
The first 13-vinyl derivatives of berberine: synthesis and antimicrobial activity
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DOI: 10.1007/s10593-019-02589-0
Abstract: A method for the synthesis of berberine 13-vinyl derivatives has been developed consisting of an initial reaction of triethyl orthoformate with CH acids in the presence of catalytic amounts of p-toluenesulfonic acid followed by the… read more here.
Keywords: vinyl derivatives; antimicrobial activity; first vinyl; derivatives berberine ... See more keywords
Synthesis and Antimicrobial Activity of Dihydrobetulin N-Acetylglucosaminides
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DOI: 10.1007/s10600-017-2210-1
Abstract: Dihydrobetulin N-acetylglucosaminides were synthesized for the first time. A study of their antimicrobial activity against a standard set of Gram-positive and Gram-negative bacteria and fungi showed highly selective bacteriostatic activity for glycosides 9 and 13… read more here.
Keywords: dihydrobetulin acetylglucosaminides; antimicrobial activity; synthesis antimicrobial; activity ... See more keywords
Synthesis and antimicrobial evaluation of new glucosylimino thiazole derivatives
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DOI: 10.1007/s13738-019-01617-2
Abstract: Abstractp-Sulphonic-N-propionyl aniline 3 was produced from sulphanilic acid with propionic acid under reflux for 2 h, then the compound 3 reacted with thionyl chloride and the corresponding imidoyl chloride 4 was obtained. When imidoyl chloride 4… read more here.
Keywords: antimicrobial evaluation; evaluation new; synthesis antimicrobial; new glucosylimino ... See more keywords