Synthesis and antinociceptive activity of four 1H‐isoindolo‐1,3(2H)‐diones
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DOI: 10.1002/ardp.202100423
Abstract: The present study aimed to design and synthesize a series of 2‐hydroxy‐3‐(4‐aryl‐1‐piperazinyl)propyl phthalimide derivatives, which are analogs of 1H‐pyrrolo[3,4‐c]pyridine‐1,3(2H)‐dione derivatives with proven analgesic effect. In accordance with the basic principle proposed by Lipinski's rule, the… read more here.
Keywords: antinociceptive activity; four isoindolo; synthesis antinociceptive; isoindolo diones ... See more keywords