Synthesis and antiplasmodial activity of purine-based C-nucleoside analogues.
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DOI: 10.1039/c8md00098k
Abstract: A series of homologous C-nucleoside mimics have been synthesized via an efficient and facile synthetic protocol involving the conjugate addition of purine to sugar derived olefinic ester in good yields. The synthesized compounds were evaluated… read more here.
Keywords: antiplasmodial activity; activity purine; purine based; synthesis antiplasmodial ... See more keywords
Synthesis and Antiplasmodial Activity of Bisindolylcyclobutenediones
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DOI: 10.3390/molecules26164739
Abstract: Malaria is one of the most dangerous infectious diseases. Because the causative Plasmodium parasites have developed resistances against virtually all established antimalarial drugs, novel antiplasmodial agents are required. In order to target plasmodial kinases, novel… read more here.
Keywords: antiplasmodial activity; activity bisindolylcyclobutenediones; target; synthesis antiplasmodial ... See more keywords