Structure‐Based Design and In‐Flow Synthesis of Aromatic Endoperoxides Acting as Oxygen Releasing Agents
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202400861
Abstract: Hypoxia occurs in different pathological settings as a consequence of poor vascularization, and it results in reduced efficacy of some current nosocomial treatments i.e. chemotherapy and photodynamic therapy. In order to overcome these boundaries, aromatic… read more here.
Keywords: synthesis aromatic; oxygen releasing; oxygen; releasing agents ... See more keywords
A Formal (4 + 2) Cycloaddition of Phosphorus Ylides: Synthesis of Aromatic and Heteroaromatic 1,2-Diesters and Diones.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01234
Abstract: Heteroarylmethylenephosphorus ylides underwent Michael addition with alkynediones and alkynediesters, followed by intramolecular cyclization and elimination of triphenylphosphine oxide to afford 1,2-diaroylbenzenes and 1,2-alkoxycarbonylcarbo- and heterocycles. The analogous (4 + 2) cycloaddition led to the formation… read more here.
Keywords: phosphorus ylides; ylides synthesis; cycloaddition phosphorus; formal cycloaddition ... See more keywords
Iron-Promoted Decarboxylation of Arylacetic Acids for the Synthesis of Aromatic Nitriles with Sodium Nitrite as the Nitrogen Source
Sign Up to like & getrecommendations! Published in 2020 at "Synlett"
DOI: 10.1055/s-0040-1707300
Abstract: A new and effective method was developed for the synthesis of aromatic nitriles from arylacetic acids by using NaNO2 as the nitrogen source and Fe(OTf)3 as the promoter at 50 °C. A series of arylacetic… read more here.
Keywords: aromatic nitriles; synthesis aromatic; nitrogen source; arylacetic acids ... See more keywords