A Formal (4 + 2) Cycloaddition of Phosphorus Ylides: Synthesis of Aromatic and Heteroaromatic 1,2-Diesters and Diones.
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DOI: 10.1021/acs.orglett.2c01234
Abstract: Heteroarylmethylenephosphorus ylides underwent Michael addition with alkynediones and alkynediesters, followed by intramolecular cyclization and elimination of triphenylphosphine oxide to afford 1,2-diaroylbenzenes and 1,2-alkoxycarbonylcarbo- and heterocycles. The analogous (4 + 2) cycloaddition led to the formation… read more here.
Keywords: phosphorus ylides; ylides synthesis; cycloaddition phosphorus; formal cycloaddition ... See more keywords
Iron-Promoted Decarboxylation of Arylacetic Acids for the Synthesis of Aromatic Nitriles with Sodium Nitrite as the Nitrogen Source
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DOI: 10.1055/s-0040-1707300
Abstract: A new and effective method was developed for the synthesis of aromatic nitriles from arylacetic acids by using NaNO2 as the nitrogen source and Fe(OTf)3 as the promoter at 50 °C. A series of arylacetic… read more here.
Keywords: aromatic nitriles; synthesis aromatic; nitrogen source; arylacetic acids ... See more keywords