Catalyst-Controlled Stereodivergent Synthesis of Atropisomeric Multiaxis Systems
Sign Up to like & getrecommendations! Published in 2018 at "ACS Central Science"
DOI: 10.1021/acscentsci.8b00204
Abstract: Molecular scaffolds with multiple rotationally restricted bonds allow a precise spatial positioning of functional groups. However, their synthesis requires methods addressing the configuration of each stereogenic axis. We report here a catalyst-stereocontrolled synthesis of atropisomeric… read more here.
Keywords: synthesis atropisomeric; multiaxis systems; atropisomeric multiaxis; catalyst controlled ... See more keywords
Enantioselective Synthesis of Atropisomeric Anilides via Pd(II)-Catalyzed Asymmetric C-H Olefination.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c09400
Abstract: Atropisomeric anilides have received tremendous attention as a novel class of chiral compounds possessing restricted rotation around an N-aryl chiral axis. However, in sharp contrast to the well-studied synthesis of biaryl atropisomers, the catalytic asymmetric… read more here.
Keywords: catalyzed asymmetric; via catalyzed; atropisomeric anilides; synthesis atropisomeric ... See more keywords
Catalytic enantioselective synthesis of atropisomeric biaryls by a cation-directed O-alkylation
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DOI: 10.1038/nchem.2710
Abstract: Axially chiral biaryls, as exemplified by 1,1′-bi-2-naphthol (BINOL), are key components of catalysts, natural products and medicines. These materials are synthesized conventionally in enantioenriched form through metal-mediated cross coupling, de novo construction of an aromatic… read more here.
Keywords: biaryls; synthesis atropisomeric; biaryls cation; alkylation ... See more keywords
Synthesis of atropisomeric phosphino-triazoles and their corresponding gold(I) complexes
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00322a
Abstract: The synthesis of atropisomeric phoshino-triazoles is disclosed. It was found that intoduction of a phosphine functionality onto the 5-position of a 1,2,3-triazole ring the rotation around a triazole-aryl bond could... read more here.
Keywords: synthesis atropisomeric; gold complexes; triazoles corresponding; corresponding gold ... See more keywords