Catalytic synthesis of bioactive 2H-chromene alcohols from (−)-isopulegol and acetone on sulfonated clays
Sign Up to like & getrecommendations! Published in 2020 at "Reaction Kinetics, Mechanisms and Catalysis"
DOI: 10.1007/s11144-020-01740-9
Abstract: Condensation of (−)-isopulegol with acetone was investigated at 25–40 °C over clay based materials (K10, cloisite Na+ and halloysite nanotubes) modified with sulfonic acid groups by one-pot sulfonation with chlorosulfonic acid or via organosilylation with… read more here.
Keywords: isopulegol acetone; bioactive chromene; chromene alcohols; catalytic synthesis ... See more keywords
Synthesis of bioactive glass using cellulose nano fibre template.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2022.105174
Abstract: This study introduces a templating approach using a cellulosic suspension to create a porous SiO2-CaO-P2O5-Na2O bioactive glass material. Sol-gel approach was used as the synthesis method. Carbon nanofibers in suspension form was used as the… read more here.
Keywords: glass; synthesis bioactive; using cellulose; template ... See more keywords
Synthesis of Bioactive Complex Small Molecule-Ciprofloxacin Conjugates and Evaluation of Their Antibacterial Activity.
Sign Up to like & getrecommendations! Published in 2020 at "ACS combinatorial science"
DOI: 10.1021/acscombsci.0c00060
Abstract: Conjugates between pharmaceuticals and small molecules enable access to a vast chemical space required for the discovery of new lead molecules with modified therapeutic potential. However, the dearth of specific chemical reactions that are capable… read more here.
Keywords: ciprofloxacin conjugates; antibacterial activity; ciprofloxacin; synthesis bioactive ... See more keywords
Synthesis of bioactive fluoropyrrolidines via copper(i)-catalysed asymmetric 1,3-dipolar cycloaddition of azomethine ylides
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d1sc04595d
Abstract: Chiral pyrrolidinyl units are important building blocks in biologically active natural products and drugs, and the development of efficient methods for the synthesis of diverse structured pyrrolidine derivatives is of great importance. Meanwhile, incorporating fluorine… read more here.
Keywords: azomethine ylides; cycloaddition azomethine; dipolar cycloaddition; synthesis bioactive ... See more keywords
Synthesis of bioactive heterocycles using reusable heterogeneous catalyst HClO4–SiO2 under solvent-free conditions
Sign Up to like & getrecommendations! Published in 2018 at "Green Chemistry Letters and Reviews"
DOI: 10.1080/17518253.2018.1510991
Abstract: ABSTRACT We are reporting a simple, efficient and green protocol for the synthesis of chromenes and dihydropyrimidines (products of Knoevenagel and Biginelli reaction, respectively) by the use of silica-supported perchloric acid (HClO4–SiO2) as an effective… read more here.
Keywords: bioactive heterocycles; hclo4 sio2; synthesis bioactive; catalyst ... See more keywords
Synthesis of bioactive natural products and their analogs at room temperature – an update
Sign Up to like & getrecommendations! Published in 2022 at "Physical Sciences Reviews"
DOI: 10.1515/psr-2021-0094
Abstract: Abstract Sustainability is a concept that is employed to distinguish methods and procedures that can ensure the long-term productivity of the environment as it includes environmental, social, and economic dimensions. New generations can live on… read more here.
Keywords: natural products; chemistry; synthesis bioactive; room temperature ... See more keywords
A Facile Synthesis of Bioactive Five- and Six-membered N-heterocyclic Aromatic Compounds Using AlCoFe2O4 as a Green Catalyst.
Sign Up to like & getrecommendations! Published in 2022 at "Acta chimica Slovenica"
DOI: 10.17344/acsi.2021.7021
Abstract: Nitrogen-containing heterocycles have been extensively studied due to their broad biological and pharmaceutical applications. In this study, we synthesized five- and six-membered nitrogen-containing rings through one-pot multicomponent reaction using an aluminium-doped cobalt ferrite nano-catalyst. The… read more here.
Keywords: five six; facile synthesis; catalyst; synthesis bioactive ... See more keywords
The Art of Total Synthesis of Bioactive Natural Products via Microwaves
Sign Up to like & getrecommendations! Published in 2021 at "Current Organic Chemistry"
DOI: 10.2174/1385272825666210303112302
Abstract: Natural products are the most effective source of potential drug leads. The total synthesis of bioactive natural products plays a crucial role in confirming the hypothetical complex structure of natural products in the laboratory. The… read more here.
Keywords: microwave irradiation; natural products; total synthesis; synthesis bioactive ... See more keywords
Multicomponent Reactions for the Synthesis of Bioactive Compounds: A Review.
Sign Up to like & getrecommendations! Published in 2019 at "Current organic synthesis"
DOI: 10.2174/1570179416666190718153703
Abstract: Multicomponent reactions (MCRs) are composed of three or more reagents in which the final product has all or most of the carbon atoms from its starting materials. These reactions represent, in the medicinal chemistry context,… read more here.
Keywords: multicomponent reactions; reactions synthesis; chemistry; compounds review ... See more keywords
Room Temperature Synthesis of Bioactive 1,2,4-Oxadiazoles
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065406
Abstract: 1,2,4-Oxadiazole is an essential motif in drug discovery represented in many experimental, investigational, and marketed drugs. This review covers synthetic methods that allow the conversion of different types of organic compounds into 1,2,4-oxadiazole at ambient… read more here.
Keywords: temperature synthesis; synthesis; temperature; synthesis bioactive ... See more keywords
Synthesis of Bioactive Silver Nanoparticles Using New Bacterial Strains from an Antarctic Consortium
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20090558
Abstract: In this study, we report on the synthesis of silver nanoparticles (AgNPs) achieved by using three bacterial strains Rhodococcus, Brevundimonas and Bacillus as reducing and capping agents, newly isolated from a consortium associated with the… read more here.
Keywords: bacterial strains; bioactive silver; silver nanoparticles; synthesis bioactive ... See more keywords