Metal free green protocol for the synthesis of bis-spiro piperidine and pyrimidine derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Research on Chemical Intermediates"
DOI: 10.1007/s11164-018-3310-7
Abstract: A highly efficient one-pot three-component synthesis of bis-spiro piperidine and pyrimidine derivatives has been reported by performing the reaction of formaldehyde, aromatic aniline and 1,3-dicarbonyl compounds. This reaction was carried out at room temperature in… read more here.
Keywords: pyrimidine derivatives; synthesis bis; piperidine pyrimidine; reaction ... See more keywords
Chemoselective synthesis of bis(indolyl)methanes using sulfonic acid-functionalized chitosan
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Papers"
DOI: 10.1007/s11696-019-00846-2
Abstract: Herein, we describe the electrophilic substitution reaction of indole with aldehydes and ketone using sulphonic acid functional group containing chitosan for the synthesis of bis(indolyl)methanes. The reaction is chemoselective affording a product from aldehydes and… read more here.
Keywords: indolyl methanes; synthesis bis; bis indolyl;
V2O5/SiO2 as a Heterogeneous Catalyst in the Synthesis of bis(indolyl)methanes Under Solvent Free Condition
Sign Up to like & getrecommendations! Published in 2017 at "Silicon"
DOI: 10.1007/s12633-016-9515-8
Abstract: The heterogeneous catalyst of V2O5/SiO2 was prepared and characterized with Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscopy. XRD of the silicon dioxide used reveals the amorphous nature while the spectrum… read more here.
Keywords: v2o5 sio2; condition; synthesis bis; catalyst ... See more keywords
Green, unexpected synthesis of bis-coumarin derivatives as potent anti-bacterial and anti-inflammatory agents.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.10.072
Abstract: A green and efficient protocol has been developed and a series of coumarin based pyrano[3,2-c]chromene derivatives (2) have been synthesized using multi-component reaction (MCR) approach. Unexpected 3-coumarinyl-3-pyrazolylpropanoic acids (3) and C4-C4 chromenes (5) have been… read more here.
Keywords: anti inflammatory; coumarin; green unexpected; unexpected synthesis ... See more keywords
Regioselective competitive synthesis of 3,5-bis(het) aryl pyrrole-2-carboxylates/carbonitriles vs. β-enaminones from β-thioxoketones
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.153373
Abstract: Abstract An easily adaptable protocol for the synthesis of 3,5-bis(het)aryl-2-carboxylate/nitrile pyrroles and the related 2,3,5-tri(het)aryl-pyrroles with complementary regioselectivity from the corresponding 1,3-bis(het)aryl-1,3-monothio diketones or β-enaminone precursors has been reported. Initially, regioselective base catalyzed condensation of… read more here.
Keywords: synthesis bis; bis het; het; het aryl ... See more keywords
NH2OH-HCl-Mediated Umpolung α-Methylsulfonylation of α-Sulfonyl Ketones with Methylsulfoxides: Synthesis of α,β-Bis-sulfonyl Arylketones.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b00422
Abstract: In this paper, a novel and efficient route for the synthesis of α,β-bis-sulfonyl arylketones via an NH2OH-HCl-mediated intermolecular umpolung α-methylsulfonylation of α-sulfonyl ketones with methylsulfoxides is described. A plausible mechanism is proposed and discussed. Various… read more here.
Keywords: nh2oh hcl; bis sulfonyl; sulfonyl; synthesis bis ... See more keywords
Atropselective Synthesis of N,C-Bis(diphenylphosphanes) from Bridged 2-Arylindoles Based on Effective Point-to-Axial Asymmetric Inductions after an Unusual Dilithiation ⊥.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03896
Abstract: An asymmetric methanolysis of glutaric anhydride and 6 ensuing steps gave veratrol-annulated dimethylcyclo-heptenone diastereomers with 99% ee; ring closures occurred by Friedel-Crafts acylations of carboxylic acids obtained by stereospecific hydrogenolyses of a pair of diastereomeric… read more here.
Keywords: bis diphenylphosphanes; diphenylphosphanes bridged; arylindoles based; synthesis bis ... See more keywords
Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c00323
Abstract: The insertion of selenium was achieved in the form of mono-selenides and di-selenides for the preparation of novel bis-heterocyclic compounds. This method is more general and provides scaffold diversity with high yields of products. The… read more here.
Keywords: heterocycles via; bis heterocycles; selective synthesis; selenylation ... See more keywords
Supported Iridium Catalyst for the Green Synthesis of 3,3′-Bis(indolyl)methanes Using Methanol As the Bridging Methylene Source
Sign Up to like & getrecommendations! Published in 2019 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.9b00094
Abstract: The first example of a heterogeneous catalyst based on hydrotalcite-derived Mg–Al oxides supported iridium (Ir/MgxAlO) for activation of methanol in the synthesis of bis(indolyl)methanes (BIMs) is reported. In this clean and reusable iridium-based catalytic system,… read more here.
Keywords: synthesis; indolyl methanes; supported iridium; catalyst ... See more keywords
Synthesis of bis(trithio)phosphines by oxidative transfer of phosphorus(i).
Sign Up to like & getrecommendations! Published in 2017 at "Dalton transactions"
DOI: 10.1039/c7dt01345k
Abstract: The synthesis of novel bis(trithio)phosphines is achieved by oxidative addition of tetrathiocins to the phosphorus(i) reagent [PIdppe][Br] in good yields under ambient conditions. These bis(trithio)phosphines and the related intermediate diphosphine species are characterized by X-ray… read more here.
Keywords: bis trithio; synthesis bis; trithio phosphines; phosphines oxidative ... See more keywords
Synthesis of bis-(benzocyclohexan-ketoimino) Ni(II) with different electron groups and their catalytic copolymerization of norbornene and polar norbornene
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra09944d
Abstract: Four N,O-chelating type bidentate ligand nickel(II) complexes, Ni{C10H8(O)C[ArN]CH3}2, two of them containing electron-donating groups (Ni1: Ar = p-PhCH3, Ni2: Ar = p-PhOCH3) and another two containing electron-withdrawing groups (Ni3: Ar = p-PhF, Ni4: Ar =… read more here.
Keywords: electron withdrawing; bis benzocyclohexan; copolymerization norbornene; synthesis bis ... See more keywords