Quantitative Analysis of NAD Synthesis-Breakdown Fluxes.
Sign Up to like & getrecommendations! Published in 2018 at "Cell metabolism"
DOI: 10.1016/j.cmet.2018.03.018
Abstract: The redox cofactor nicotinamide adenine dinucleotide (NAD) plays a central role in metabolism and is a substrate for signaling enzymes including poly-ADP-ribose-polymerases (PARPs) and sirtuins. NAD concentration falls during aging, which has triggered intense interest… read more here.
Keywords: synthesis breakdown; nad synthesis; metabolism; analysis ... See more keywords
Synthesis and breakdown of universal metabolic precursors promoted by iron
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DOI: 10.1038/s41586-019-1151-1
Abstract: Life builds its molecules from carbon dioxide (CO2) and breaks them back down again through the intermediacy of just five metabolites, which are the universal hubs of biochemistry1. However, it is unclear how core biological… read more here.
Keywords: synthesis breakdown; metabolic precursors; universal metabolic; breakdown universal ... See more keywords