Expedited Total Synthesis of (±)-Brevianamide A via the Strategic Use of Gold(I) Catalysis.
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DOI: 10.1021/acs.orglett.2c02971
Abstract: Two concise and complementary routes to the polycyclic alkaloid (±)-brevianamide A from readily available amino acid building blocks are presented. Key to the synthesis is the strategic use of a gold(I)-catalyzed cascade process that quickly… read more here.
Keywords: synthesis brevianamide; gold catalysis; use gold; synthesis ... See more keywords
Unified total synthesis of the brevianamide alkaloids enabled by chemical investigations into their biosynthesis
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DOI: 10.1039/d1sc05801k
Abstract: The bicyclo[2.2.2]diazaoctane alkaloids are a vast group of natural products which have been the focus of attention from the scientific community for several decades. This interest stems from their broad range of biological activities, their… read more here.
Keywords: biosynthesis; bicyclo diazaoctane; unified total; synthesis ... See more keywords