Iron(III) chloride-catalyzed synthesis of 3-carboxy-2,5-disubstituted furans from γ-alkynyl aryl- and alkylketones
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DOI: 10.1016/j.tet.2017.04.030
Abstract: Abstract A mild, catalytic method for the synthesis of 3-carboxy-2,5-disubstituted furans is reported proceeding via a 5-exo-dig cycloisomerization reaction. The iron(III) chloride-catalyzed transformation of aryl- and alkyl β-ketoesters enables synthetic access to functionalized furan core… read more here.
Keywords: synthesis carboxy; iii chloride; carboxy disubstituted; disubstituted furans ... See more keywords