Benchtop 19F nuclear magnetic resonance spectroscopy enabled kinetic studies and optimization of the synthesis of carmofur
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DOI: 10.1139/cjc-2022-0266
Abstract: Carmofur, a 5-fluorouracil derivative, was initially developed as an antineoplastic agent to treat colorectal cancer. Through drug repurposing efforts, it has been identified as a potent covalent inhibitor of the main protease of SARS-CoV-2 (Mpro),… read more here.
Keywords: benchtop 19f; spectroscopy; synthesis; synthesis carmofur ... See more keywords