Synthesis, crystal structure, and ADME prediction studies of novel imidazopyrimidines as antibacterial and cytotoxic agents
Sign Up to like & getrecommendations! Published in 2020 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201900271
Abstract: In the present study, a novel series of polyfunctionalized imidazopyrimidines 6a–u and 9a–d were efficiently constructed by a domino reaction between 2‐imino‐6‐substituted‐2,3‐dihydropyrimidin‐4(1H)‐ones 4a–d or 8a–c and 2‐bromoacetophenones 5a–i under mild basic conditions. The synthesized series… read more here.
Keywords: structure adme; crystal structure; adme prediction; activity ... See more keywords
Synthesis, crystal structure, anti-HIV, and antiproliferative activity of new pyrazolylthiazole derivatives
Sign Up to like & getrecommendations! Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-1963-1
Abstract: The development of new HIV-1 non-nucleoside reverse transcriptase inhibitors offers the possibility of generating novel structures of increased potency. Based on the bioisosteric principle, new series of N′-benzylidene-2-(5-(4-chlorophenyl)-3-phenyl-4,5-dihydropyrazol-1-yl)thiazole-4-carbohydrazide schiff bases 5a–x containing 1,3-thiazole clubbed with… read more here.
Keywords: crystal structure; hiv; antiproliferative activity; activity ... See more keywords
Synthesis, Crystal Structure and Thermal Property of Two New Coordination Polymers with Ligands Containing Both N and O Donors
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DOI: 10.1007/s10870-019-00785-6
Abstract: Abstract Two new metal–organic coordination polymer frameworks formulated as, {[Co(nta)]·H 3 O + } n ( 1 ), and {[Zn(ina)Cl 2 ]·H 3 O + ·H 2 O} n ( 2 ) (nta = nitriliotriacetic acid, ina = isonicotinate),… read more here.
Keywords: structure thermal; crystal structure; coordination; two new ... See more keywords
Synthesis and Crystal Structures of Two Metal–Radical Complexes
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DOI: 10.1007/s10870-019-00797-2
Abstract: Two new M(II)–radical complexes [M(hfac)2(NITPhSCH3)2] (M = Co (1), Mn (2); NITPhSCH3 = 4′-thiomethylphenyl-4,4,5,5-tetramethyl-imidazoline-1-oxyl-3-oxide; and hfac = hexafluoroacetylacetonate) have been synthesized and characterized by X-ray diffraction analysis, element analyses, IR and UV–Visible spectroscopy. X-ray analysis reveals that the structures of both… read more here.
Keywords: two metal; structures two; metal radical; crystal structures ... See more keywords
Synthesis, Crystal Structure, Electrochemical and Catalytic Properties of Hybrid Polyoxomolybdate Clusters-Based Terbium Complex
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Inorganic and Organometallic Polymers and Materials"
DOI: 10.1007/s10904-017-0511-2
Abstract: The inorganic–organic compound based on polyoxomolybdate [Tb(C2H6SO)8][PMo12 O40]·2C2H6SO·½H2O (I) has been isolated and structurally characterized by single-crystal X-ray molecular structure, IR spectra, thermogravimetric analysis and cyclic voltammetry measurements. The catalytic activities of (I) were also… read more here.
Keywords: crystal structure; structure electrochemical; electrochemical catalytic; structure ... See more keywords
High-pressure synthesis, crystal structure and physical properties of a new Cr-based arsenide La3CrAs5
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DOI: 10.1007/s40843-020-1344-x
Abstract: In La-Cr-As system, the first ternary compound La3CrAs5 has been successfully synthesized under high-pressure and high-temperature conditions. La3CrAs5 crystallizes into a hexagonal Hf5Sn3Cu-anti type structure with a space group of P63/mcm (No. 193) and lattice… read more here.
Keywords: crystal structure; pressure synthesis; high pressure; structure ... See more keywords
Synthesis, crystal structure, luminescent properties and antibacterial activities of zinc complexes with bipyridyl and salicylate ligands
Sign Up to like & getrecommendations! Published in 2018 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2017.11.053
Abstract: Abstract Two novel coordination complexes having salicylate and bidentate rigid organodiamine ligands, namely, [Zn(μ-bpp)2(Sal)2]n (1) and [{Zn(Sal)2}2(μ-bpe)]2 (2) [bpp = 1,3-bis(4-pyridyl)propane, bpe = 1,2-bis(4-pyridyl)ethane, and Sal− = salicylate anion] were synthesized under solvothermal condition. The complexes were investigated by single crystal… read more here.
Keywords: crystal structure; structure luminescent; luminescent properties; spectroscopy ... See more keywords
Synthesis, crystal structure and magnetic properties of a cyanide-bridged one-dimensional FeIIICoII metamagnet
Sign Up to like & getrecommendations! Published in 2018 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2018.05.030
Abstract: Abstract A new cyanide-bridged FeIIICoII bimetallic complex {[Fe(Tp)(CN)3Co(LN3O2)]ClO4·2H2O}n (Tp− = hydrotris(pyrazolyl)borate, LN3O2 = 2,13-dimethyl-6,9-dioxa-3,12,18-triaza-bicyclo[12.3.1]octadeca-1(18),2,12,14,16-pentene) (1) has been synthesized based on the building blocks of [CoII(LN3O2)(H2O)2](ClO4)2 and Bu4N[FeIII(Tp)(CN)3]. X-ray single crystal diffraction analysis shows that complex 1 has a cyanide-bridged… read more here.
Keywords: cyanide bridged; one dimensional; structure magnetic; metamagnet ... See more keywords
Synthesis, crystal structure, DNA binding and in vitro cytotoxicity studies of Zn(II) complexes derived from amino-alcohol Schiff-bases
Sign Up to like & getrecommendations! Published in 2018 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2018.06.008
Abstract: Abstract Three new zinc(II) complexes, namely, [Zn 2 (H 2 L1) 2 (OAc) 2 ] ( 1 ), [Zn 3 (H 2 L1) 2 (OAc) 4 ] ( 2 ) and {[Zn 3 (H 2… read more here.
Keywords: structure dna; crystal structure; amino; structure ... See more keywords
Synthesis, crystal structure, magnetic properties and DFT calculations of a mononuclear copper(II) complex: Relevance of halogen bonding for magnetic interaction
Sign Up to like & getrecommendations! Published in 2018 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2018.06.033
Abstract: Abstract The synthesis, crystal structure, magnetic properties and DFT calculations of a new mononuclear copper(II) complex containing a pyrazole-based ligand are reported. In the crystal structure of the [CuCl2L2] complex (L = Ethyl 5-amino-1-(4-methoxyphenyl)-1H-pyrazole-4-carboxylate), a network of… read more here.
Keywords: crystal structure; dft calculations; synthesis crystal; mononuclear copper ... See more keywords
Synthesis, crystal structure analysis, spectral characterization and nonlinear optical exploration of potent thiosemicarbazones based compounds: A DFT refine experimental study
Sign Up to like & getrecommendations! Published in 2019 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2018.10.035
Abstract: Abstract The thiosemicarbazones have exciting biological and nonlinear optical (NLO) applications. The present study reports detail experimental and computational studies of three novel ferrocene-substituted thiosemicarbazones: (E/Z)-4-benzyl-1-(1-ferrocenylethyl)thiosemicarbazones (1), (E/Z)-4-(4-chlorobenzyl)-1-(1-ferrocenyl-ethyl) thiosemicarbazone (2) and (E/Z)-4-(2-bromo benzyl)-1-(1-ferrocenylethyl)thiosemicarbazone (3). These… read more here.
Keywords: level theory; synthesis crystal; study; crystal structure ... See more keywords