Efficient synthesis of 3,4-diarylpyrrole-2-carboxylates, the key fragments of natural antimitotic agents
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DOI: 10.1007/s11172-018-2375-1
Abstract: Barton-Zard reaction of nitrostilbenes with ethyl isocyanoacetate carried out in EtOH in the presence of K2CO3 allowed us to minimize the formation of side products and to obtain 3,4-diarylpyrrole-2-carboxylates in high yields. read more here.
Keywords: fragments natural; carboxylates key; synthesis diarylpyrrole; efficient synthesis ... See more keywords