Photoredox Organocatalysis for the Enantioselective Synthesis of 1,7-Dicarbonyl Compounds.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00326
Abstract: We describe an asymmetric organocatalytic method to synthesize 1,7-dicarbonyl compounds containing a β-stereocenter. The chemistry relies on the formation of γ-keto radicals, generated upon oxidative ring opening of cyclobutanols mastered by an organic photoredox catalyst.… read more here.
Keywords: organocatalysis enantioselective; enantioselective synthesis; chemistry; synthesis dicarbonyl ... See more keywords
Two-Step Continuous Synthesis of Dicarbonyl Indoles via I2/DMSO-Promoted Oxidative Coupling: A Green and Practical Approach to Valuable Diketones from Aryl Acetaldehydes
Sign Up to like & getrecommendations! Published in 2018 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.8b01339
Abstract: A green and practical method for the synthesis of C-3 dicarbonyl indoles from aryl acetaldehydes and indoles was developed under I2/DMSO conditions, employing an assembled two-step continuous flow system. Moderate to good yields of dicarbonyl… read more here.
Keywords: green practical; aryl acetaldehydes; dicarbonyl indoles; synthesis dicarbonyl ... See more keywords
Convergent Synthesis of 1,4-Dicarbonyl Z-Alkenes through Three-Component Coupling of Alkynes, α-Diazo Sulfonium Triflate, and Water.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c12874
Abstract: We report a general protocol for the convergent synthesis of 1,4-dicarbonyl Z-alkenes form alkynes using α-diazo sulfonium triflate and water. The C═O, C═C, and C-H bonds are formed under mild conditions with a wide range… read more here.
Keywords: sulfonium triflate; diazo sulfonium; dicarbonyl alkenes; convergent synthesis ... See more keywords