Synthesis of different thio-scaffolds bearing sulfonamide with subnanomolar carbonic anhydrase II and IX inhibitory properties and X-ray investigations for their inhibitory mechanism.
Sign Up to like & getrecommendations! Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.09.028
Abstract: Several new molecules with different thio-scaffolds were designed, synthesised, and evaluated biologically as inhibitors of Carbonic Anhydrases (CAIs). The structure-activity relationship analysis identified thioether derivatives, here reported, as a potent and selective CAIs against hCA… read more here.
Keywords: bearing sulfonamide; synthesis different; thio scaffolds; scaffolds bearing ... See more keywords
Hydrothermal synthesis of different structures TiO2 and photocatalytic activity for tetracycline and Cr (VI) removal
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DOI: 10.1111/wej.12977
Abstract: Ensuring the removal of pollutants including organic and heavy metal contaminants through cost‐effective methods was crucial for mitigating toxicity risks. In this study, a facile hydrothermal method was employed to synthesize TiO2, encompassing flower‐like TiO2,… read more here.
Keywords: synthesis different; photocatalytic activity; removal; different structures ... See more keywords
Solvent-dependent chemoselective synthesis of different isoquinolinones mediated by the hypervalent iodine(III) reagent PISA
Sign Up to like & getrecommendations! Published in 2024 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.20.167
Abstract: Isoquinolinone is an important heterocyclic framework in natural products and biologically active molecules, and the efficient synthesis of this structural motif has received much attention in recent years. Herein, we report a (phenyliodonio)sulfamate (PISA)-mediated, solvent-dependent… read more here.
Keywords: pisa; solvent dependent; synthesis different; dependent chemoselective ... See more keywords