Enzyme-Catalyzed Cascade Michael/Cyclization Reaction for the Synthesis of 3,4-Dihydropyran Derivatives by Using a Protease
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DOI: 10.1007/s10562-017-2275-2
Abstract: AbstractProtease from Streptomyces griseus (SGP) as a sustainable biocatalyst was successfully applied in the Michael/cyclization reaction between dimedone and aryl or alkyl substituted α,β-unsaturated ketones or ester for the synthesis of 3,4-dihydropyran derivatives. The products… read more here.
Keywords: dihydropyran derivatives; synthesis dihydropyran; cyclization reaction;