Cholinesulfuric acid ionic liquid catalyzed an eco-friendly synthesis of 2,3-dihydroquinazolin-4(1H)-one in aqueous media
Sign Up to like & getrecommendations! Published in 2017 at "Research on Chemical Intermediates"
DOI: 10.1007/s11164-016-2849-4
Abstract: Abstract An efficient and straightforward approach to the synthesis of 2,3-dihydroquinazolin-4(1H)-one from 2-aminobenzamide and carbonyl compounds (aldehydes and ketones) using biocompatible choline sulfate-based acidic ionic liquid as a cheap and readily available catalyst in water… read more here.
Keywords: dihydroquinazolin one; ionic liquid; catalyst; synthesis dihydroquinazolin ... See more keywords
Solvent-Free, Mechanochemically Scalable Synthesis of 2,3-Dihydroquinazolin-4(1H)-one Using Brønsted Acid Catalyst
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DOI: 10.1021/acssuschemeng.9b03199
Abstract: Although the synthesis of novel N-heterocyclic molecules is extremely demanding as well as challenging, the involvement of toxic solvents often triggers environmental safety concerns, resulting in process-engineering challenges. Herein, we have demonstrated a rapid, environmentally… read more here.
Keywords: synthesis; catalyst; dihydroquinazolin one; synthesis dihydroquinazolin ... See more keywords
Efficient synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by titanium silicon oxide nanopowder in aqueous media
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DOI: 10.1080/00397911.2016.1254801
Abstract: ABSTRACT An efficient synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives is accomplished in aqueous media by a three-component reaction of isatoic anhydride, primary amines or ammonium acetate, and aldehydes catalyzed by titanium silicon oxide nanopowder. A variety of… read more here.
Keywords: aqueous media; efficient synthesis; synthesis dihydroquinazolin; catalyzed titanium ... See more keywords
Eucalyptol: An efficient, unexplored, green media for transition metal free synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives and isoxazolone derivatives
Sign Up to like & getrecommendations! Published in 2023 at "Synthetic Communications"
DOI: 10.1080/00397911.2023.2197118
Abstract: Abstract Eucalyptol or 1,8-cineole, a bio-based monoterpene, whose potential has been explored as a viable alternative reaction media for the development of several heterocyclic systems. As an eco-benign solvent eucalyptol has been found to be… read more here.
Keywords: green media; isoxazolone derivatives; transition metal; dihydroquinazolin one ... See more keywords
Uses of Anthranilic Acid for the Synthesis of Dihydroquinazolin Derivatives with Antitumor, Antiproliferative and Pim-1 kinase Activities.
Sign Up to like & getrecommendations! Published in 2018 at "Acta chimica Slovenica"
DOI: 10.17344/acsi.2017.4146
Abstract: The reaction of anthranilic acid with ethoxycarbonylisothiocyanate gave the ethyl 4-oxo-2-thioxo-1,2-dihydroquinazoline-3(4H)-carboxylate (4). The reaction of compound 4 with hydrazine hydrate and ∆-halocarbonyl derivatives was found to give either hydrazono or S-alkylated products. Heterocyclization reactions of… read more here.
Keywords: pim kinase; dihydroquinazolin derivatives; synthesis dihydroquinazolin; anthranilic acid ... See more keywords