Microwave-Assisted Synthesis of Diversely Substituted Quinoline-Based Dihydropyridopyrimidine and Dihydropyrazolopyridine Hybrids.
Sign Up to like & getrecommendations! Published in 2017 at "ACS combinatorial science"
DOI: 10.1021/acscombsci.7b00091
Abstract: An efficient, catalyst-free, and one-pot three-component procedure for the synthesis of novel and nitrogen rich dihydropyrido[2,3-d]pyrimidines and dihydro-1H-pyrazolo[3,4-b]pyridines bearing a quinoline pharmacophore fragment is provided. Reactions proceeded in DMF under microwave irradiation of three-component mixtures… read more here.
Keywords: microwave assisted; quinoline; assisted synthesis; synthesis ... See more keywords
Synthesis of Diversely Substituted Diethyl (Pyrrolidin-2-Yl)Phosphonates
Sign Up to like & getrecommendations! Published in 2025 at "Molecules"
DOI: 10.3390/molecules30092078
Abstract: Imidazoline I2 receptors (I2-IR) are untapped therapeutic targets lacking a structural description. Although the levels of I2-IR are dysregulated in a plethora of illnesses, the arsenal of ligands that can modulate I2-IR is limited. In… read more here.
Keywords: synthesis diversely; substituted diethyl; diversely substituted; diethyl pyrrolidin ... See more keywords