Synthesis of dual-action parthenolide prodrugs as potent anticancer agents.
Sign Up to like & getrecommendations! Published in 2017 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2017.01.020
Abstract: Cancer stem cells are responsible for the failure of a large number of cancer treatments and the re-emergence of cancer in patients. Parthenolide is a potent anticancer sesquiterpene lactone that is also able to kill… read more here.
Keywords: cancer; synthesis dual; parthenolide prodrugs; potent anticancer ... See more keywords
One-pot enzyme-catalyzed synthesis of dual-functional polyester macromers towards surface-active hydrophobic films
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra09828f
Abstract: Selective enzyme catalysis is a valuable tool for the processing of monomers into value-added materials. In the present study natural resources were used to retrieve an ω-hydroxy fatty acid monomer containing an epoxide functionality. A… read more here.
Keywords: synthesis dual; dual functional; one pot; functional polyester ... See more keywords
Design and synthesis of a dual imageable theranostic platinum prodrug for efficient cancer therapy
Sign Up to like & getrecommendations! Published in 2019 at "Polymer Chemistry"
DOI: 10.1039/c8py01535j
Abstract: Platinum-based chemotherapeutic agents are considered first-line treatments for various cancers but their application is limited by the lack of site specificity and severe side effects. read more here.
Keywords: dual imageable; design synthesis; imageable theranostic; synthesis dual ... See more keywords